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Article

Olaparib Inhibits Tumor Growth of Hepatoblastoma in Patient‐Derived Xenograft Models

26 May 2021

Abstract excerpt

BACKGROUND AND AIMS: Hepatoblastoma (HBL) is a devastating pediatric liver cancer with multiple treatment options, but it ultimately requires surgery for a cure. The most malicious form of HBL is a chemo-resistant aggressive tumor that is characterized by rapid growth, metastases, and poor response to treatment. Very little is known of the mechanisms of aggressive HBL, and recent focuses have been on developing...

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PMID: 34037269
DOI: 10.1002/hep.31919

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