Comparison study of differential abundance testing methods using two large Parkinson disease gut microbiome datasets derived from 16S amplicon sequencing

Abstract excerpt

BACKGROUND: Testing for differential abundance of microbes in disease is a common practice in microbiome studies. Numerous differential abundance (DA) testing methods exist and range from traditional statistical tests to methods designed for microbiome data. Comparison studies of DA testing methods have been performed, but none performed on microbiome datasets collected for the study of real, complex disease. Due...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gut microbiota and health
• Share to Infections and bacterial resistance
• Share to Parkinson's Disease Mechanisms and Treatments