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Integrated Multi‐Cohort Analysis of the Parkinson's Disease Gut Metagenome

24 Jan 2023

Abstract excerpt

BACKGROUND: The gut microbiome is altered in several neurologic disorders, including Parkinson's disease (PD). OBJECTIVES: The aim is to profile the fecal gut metagenome in PD for alterations in microbial composition, taxon abundance, metabolic pathways, and microbial gene products, and their relationship with disease progression. METHODS: Shotgun metagenomic sequencing was conducted on 244 stool donors from two...

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PMID: 36691982
DOI: 10.1002/mds.29300

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