Article
Meta-analysis of the human gut microbiome uncovers shared and distinct microbial signatures between diseases
2024-02-29
Abstract excerpt
<h4>ABSTRACT</h4> Microbiome studies have revealed gut microbiota’s potential impact on complex diseases. However, many studies often focus on one disease per cohort. We developed a meta-analysis workflow for gut microbiome profiles and analyzed shotgun metagenomic data covering 11 diseases. Using interpretable machine learning and differential abundance analysis, our findings reinforce the generalization of bina...
Topics
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- Clostridium difficile and Clostridium perfringens research
- Epigenetics and DNA Methylation
- Food Security and Health in Diverse Populations
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Inflammatory Bowel Disease
- Mycobacterium research and diagnosis
- Probiotics and Fermented Foods
Identifiers and source
- Literature Corpus work
- 5ca5e2e2-2936-5814-883a-052c5d71a421
- DOI
- 10.1101/2024.02.27.582333
