Characterizing dysbiosis of gut microbiome in PD: evidence for overabundance of opportunistic pathogens

Abstract excerpt

Abstract In Parkinson’s disease (PD), gastrointestinal features are common and often precede the motor signs. Braak and colleagues proposed that PD may start in the gut, triggered by a pathogen, and spread to the brain. Numerous studies have examined the gut microbiome in PD; all found it to be altered, but found inconsistent results on associated microorganisms. Studies to date have been small ( N = 20 to 306)...

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