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Article

Absence of interferon-λ 4 enhances spontaneous clearance of acute hepatitis C virus genotypes 1-3 infection.

Scandinavian journal of gastroenterology - 1 Jul 2021

Waldenström Jesper, Kåberg Martin, Alanko Blomé Marianne, Widell Anders, Björkman Per, Nilsson Staffan, Hammarberg Anders, Weiland Ola, Nyström Kristina, Lagging Martin

Abstract excerpt

OBJECTIVES: Absence of a functional interferon-λ 4 (IFN-λ4) gene (IFNL4) predicts spontaneous resolution of acute hepatitis C virus (HCV) infections in regions with a predominance of genotype 1, whereas variants of the inosine triphosphate pyrophosphatase (ITPase) gene (ITPA) entailing reduced activity associate with increased sustained virologic response rates following some therapeutic regimens. This study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34034600
DOI: 10.1080/00365521.2021.1925956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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