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Article

Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.

Hepatology (Baltimore, Md.) - 1 Jun 2014

Rembeck Karolina, Waldenström Jesper, Hellstrand Kristoffer, Nilsson Staffan, Nyström Kristina, Martner Anna, Lindh Magnus, Norkrans Gunnar, Westin Johan, Pedersen Court, Färkkilä Martti, Langeland Nina, Buhl Mads Rauning, Mørch Kristine, Christensen Peer Brehm, Lagging Martin

Abstract excerpt

UNLABELLED: The present study evaluated the impact of variations in the inosine triphosphate pyrophosphatase (ITPase) gene (ITPA) on treatment outcome in patients with hepatitis C virus (HCV) genotype 2/3 infection receiving peginterferon-α2a and lower, conventional 800 mg daily dose of ribavirin. Previous studies using higher, weight-based ribavirin dosing report that patients carrying polymorphisms encoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24519039
DOI: 10.1002/hep.27009

Genes

ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.PMID 24519039Read ↗

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