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Article

Behavioral fingerprints predict insecticide and anthelmintic mode of action.

Molecular systems biology - 1 May 2021

McDermott-Rouse Adam, Minga Eleni, Barlow Ida, Feriani Luigi, Harlow Philippa H, Flemming Anthony J, Brown André E X

Abstract excerpt

Novel invertebrate-killing compounds are required in agriculture and medicine to overcome resistance to existing treatments. Because insecticides and anthelmintics are discovered in phenotypic screens, a crucial step in the discovery process is determining the mode of action of hits. Visible whole-organism symptoms are combined with molecular and physiological data to determine mode of action. However, manual...

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Identifiers

PMID: 34031985
DOI: 10.15252/msb.202110267
PMCID: PMC8144879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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