Article
High-content phenotypic screening identifies novel chemistries that disrupt mosquito activity and development.
Pesticide biochemistry and physiology - 1 Mar 2022
Murgia M V, Sharan S, Kaur J, Austin W, Hagen L, Wu L, Chen L, Scott J A, Flaherty D P, Scharf M E, Watts V J, Hill C A
Abstract excerpt
New classes of chemistries are needed to control insecticide resistant populations of mosquitoes and prevent transmission of vector-borne diseases (VBDs). Organismal screens of chemical collections have played an important role in the search for new vector insecticides and the identification of active ingredients (AIs) that cause rapid mortality of mosquitoes. Advances in image-based screening offer an...
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