Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of FtsZ Inhibition on the Localization of the Penicillin Binding Proteins in Methicillin-Resistant Staphylococcus aureus

10 Jun 2021

Abstract excerpt

MRSA is a multidrug-resistant bacterial pathogen of acute clinical importance, infecting many thousands of individuals globally each year. The essential cell division protein FtsZ has been identified as an appealing target for the development of new drugs to combat MRSA infections. Through synergistic actions, FtsZ-targeting agents can sensitize MRSA to antibiotics like the β-lactams that would otherwise be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial Genetics and Biotechnology
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34031040
DOI: 10.1128/jb.00204-21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of FtsZ Inhibition on the Localization of the Penicillin Binding Proteins in Methicillin-Resistant Staphylococcus aureusPMID 34031040Read ↗

Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics.Semantic proximity Read ↗

FtsZ inhibition: A promising approach for antistaphylococcal therapySemantic proximity Read ↗

Structural Flexibility of an Inhibitor Overcomes Drug Resistance Mutations in Staphylococcus aureus FtsZ.Semantic proximity Read ↗

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity.Semantic proximity Read ↗

Therapeutic potential of FtsZ inhibition: a patent perspectiveSemantic proximity Read ↗

Doxorubicin inhibits E. coli division by interacting at a novel site in FtsZ.Semantic proximity Read ↗

Homology modeling, virtual screening, molecular docking, and dynamics studies for discovering Staphylococcus epidermidis FtsZ inhibitorsSemantic proximity Read ↗

Inhibiting the growth of methicillin-resistant Staphylococcus aureus in vitro with antisense peptide nucleic acid conjugates targeting the ftsZ geneSemantic proximity Read ↗

<i>Staphylococcus aureus</i> FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsBSemantic proximity Read ↗

Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1Semantic proximity Read ↗

The ClpX chaperone controls the <i>Staphylococcus aureus</i> cell cycle but can be bypassed by β-lactam antibioticsSemantic proximity Read ↗

Identification of a New FtsZ Inhibitor by Virtual Screening, Mechanistic Insights, and Structure–Activity Relationship AnalysesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.