Article
Studying Neuronal Biology Using Spinning Disc Confocal Microscopy.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Manzella-Lapeira Javier, Brzostowski Joseph, Serra-Vinardell Jenny
Abstract excerpt
Cytoskeletal integrity is essential for neuronal complexity and functionality. Certain inherited neurological diseases are associated with mutated genes that directly or indirectly compromise cytoskeletal stability. While the large size and complexity of the neurons grown in culture poses certain challenges for imaging, live-cell imaging is an excellent approach to determine the morphological consequences of such...
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