Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hmg1 mutations in Aspergillus fumigatus and their contribution to triazole susceptibility.

Medical mycology - 4 Oct 2021

Arai Teppei, Umeyama Takashi, Majima Hidetaka, Inukai Tatsuya, Watanabe Akira, Miyazaki Yoshitsugu, Kamei Katsuhiko

Abstract excerpt

Triazole-resistant Aspergillus fumigatus is a global health concern. In general, each triazole resistance pattern caused by the specified amino acid substitution of Cyp51A has a typical pattern depending on the mutation site. We evaluated the contribution of both Cyp51A and Hmg1 mutations to atypical triazole resistance in A. fumigatus. We used clinical triazole-resistant A. fumigatus strains collected in Japan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Aspergillus fumigatus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Drug Resistance, Fungal

Share to Fungal Proteins

Share to Microbial Sensitivity Tests

Share to Mutation

Share to Triazoles

Source

Identifiers

PMID: 34019670
DOI: 10.1093/mmy/myab026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hmg1 mutations in Aspergillus fumigatus and their contribution to triazole susceptibility.PMID 34019670Read ↗

Hmg1 Gene Mutation Prevalence in Triazole-Resistant Aspergillus fumigatus Clinical IsolatesSemantic proximity Read ↗

Efficient Generation of Multiple Seamless Point Mutations Conferring Triazole Resistance in Aspergillus fumigatusSemantic proximity Read ↗

Triazole phenotypes and genotypic characterization of clinical Aspergillus fumigatus isolates in China.Semantic proximity Read ↗

Genome-Wide Association Analysis for Triazole Resistance in Aspergillus fumigatusSemantic proximity Read ↗

<i>hapE</i> and <i>hmg1</i> Mutations Are Drivers of <i>cyp51A</i> -Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical IsolateSemantic proximity Read ↗

Triazole resistance surveillance in Aspergillus fumigatus.Semantic proximity Read ↗

Increased triazole-resistance and cyp51A mutations in Aspergillus fumigatus after selection with a combination of the triazole fungicides difenoconazole and propiconazole.Semantic proximity Read ↗

Directed evolution of the pathogenic mold Aspergillus fumigatus reveals novel genes contributing to triazole resistance.Semantic proximity Read ↗

Emergence of W272C Substitution in Hmg1 in a Triazole-Resistant Isolate of Aspergillus fumigatus from a Chinese Patient with Chronic Cavitary Pulmonary Aspergillosis.Semantic proximity Read ↗

Prevalence of cyp51A variants in a US collection of Aspergillus fumigatus clinical isolates and comparative analysis of their contribution to triazole antifungal resistance.Semantic proximity Read ↗

Azole Resistance and cyp51A Mutation of Aspergillus fumigatus in a Tertiary Referral Hospital in TaiwanSemantic proximity Read ↗

A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.