Article
Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa.
Genes and immunity - 1 Mar 2016
Lassaunière R, Tiemessen C T
Abstract excerpt
This study set out to comprehensively investigate all known functional FcγR variants in South African Black and Caucasian individuals. Population diversity was further assessed using data from the 1000 Genomes Project. In our cohort, Black South Africans neither possessed the haplotypes previously associated with increased surface densities of FcγRIIb and FcγRIIIa nor the FCGR2C haplotype recently associated with...
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