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Identification of key genes and pathways associated with cholangiocarcinoma development based on weighted gene correlation network analysis

31 Oct 2019

Abstract excerpt

BACKGROUND: As the most frequently occurred tumor in biliary tract, cholangiocarcinoma (CCA) is mainly characterized by its late diagnosis and poor outcome. It is therefore urgent to identify specific genes and pathways associated with its progression and prognosis. MATERIALS AND METHODS: The differentially expressed genes in The Cancer Genome Atlas were analyzed to build the co-expression network by Weighted...

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PMID: 31687280
DOI: 10.7717/peerj.7968

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