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Developmentally regulated signaling pathways in glioma invasion

18 Aug 2017

Abstract excerpt

Malignant gliomas are the most common, infiltrative, and lethal primary brain tumors affecting the adult population. The grim prognosis for this disease is due to a combination of the presence of highly invasive tumor cells that escape surgical resection and the presence of a population of therapy-resistant cancer stem cells found within these tumors. Several studies suggest that glioma cells have cleverly...

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PMID: 28821904
DOI: 10.1007/s00018-017-2608-8

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