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Article

Trajectories of depression symptoms over time differ by APOE4 genotype in older adults with type 2 diabetes.

International journal of geriatric psychiatry - 1 Oct 2021

Lavie Inbar, Beeri Michal Schnaider, Berman Yuval, Schwartz Yonathan, Soleimani Laili, Heymann Anthony, Ravona-Springer Ramit

Abstract excerpt

OBJECTIVES: The APOE-ε4 genotype has been associated with old-age depression, but this relationship has been rarely investigated in type 2 diabetes (T2D) older adults, who are at significantly increased risk for depression, a major contributor to T2D complications. We examined whether trajectories of depression symptoms over time differ by APOE-ε4 genotype in older adults with T2D. METHODS: Participants (n = 754...

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Identifiers

PMID: 34010987
DOI: 10.1002/gps.5583
PMCID: PMC8845090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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