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Article

Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study.

Scientific reports - 9 May 2017

Garasia Sophiya, Samaan Zainab, Gerstein Hertzel C, Engert James C, Mohan Viswanathan, Diaz Rafael, Anand Sonia S, Meyre David

Abstract excerpt

We assessed the association between depression status and prevalent and incident type 2 diabetes (T2D) as well as the interaction between depression and a genetic risk score (GS) based on 20 T2D single-nucleotide polymorphisms (SNPs) in a multi-ethnic longitudinal study. We studied 17,375 participants at risk for dysglycemia. All participants had genotypic and phenotypic data collected at baseline and 9,930...

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Case-Control Studies
Depression
Diabetes Mellitus, Type 2
Ethnicity
Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Longitudinal Studies

Quantitative Trait, Heritable

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Identifiers

PMID: 28487510
DOI: 10.1038/s41598-017-01406-y
PMCID: PMC5431642

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