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Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood

19 May 2021

Abstract excerpt

BACKGROUND: DNA methylation markers have been associated with lung cancer risk and may identify aetiologically relevant genomic regions, or alternatively, be markers of disease risk factors or biological processes associated with disease development. METHODS: In a nested case-control study, we measured blood leukocyte DNA methylation levels in pre-diagnostic samples collected from 430 participants (208 cases; 222...

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PMID: 34008478
DOI: 10.1080/15592294.2021.1923615

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