Article
Pancreatic cancer: BRCA mutation and personalized treatment.
Expert review of anticancer therapy - 1 Jan 2015
Luo Guopei, Lu Yu, Jin Kaizhou, Cheng He, Guo Meng, Liu Zuqiang, Long Jiang, Liu Chen, Ni Quanxing, Yu Xianjun
Abstract excerpt
The highly heterozygous nature of pancreatic cancer is partially responsible for its therapeutic ineffectiveness and resistance. Therefore, the ability to identify subgroups of pancreatic cancer with unique biological characteristics and treatment response is urgently needed. In addition to breast and ovarian cancer, pancreatic cancer is the third most common cancer type that is related to the early onset (BRCA)...
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