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Advances in therapeutic options for newly diagnosed, high-risk AML patients

1 Jan 2021

Abstract excerpt

Acute myeloid leukemia (AML) is an aggressive malignancy characterized by clonal proliferation of neoplastic immature precursor cells. AML impacts older adults and has a poor prognosis. Despite recent advances in treatment, AML is complex, with both genetic and epigenetic aberrations in the malignant clone and elaborate interactions with its microenvironment. We are now able to stratify patients on the basis of...

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PMID: 33995985
DOI: 10.1177/20406207211001138

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