Article
Evolving treatment strategies in patients with high-risk acute myeloid leukemia.
Leukemia & lymphoma - 1 Nov 2014
Schiller Gary J
Abstract excerpt
Acute myeloid leukemia (AML) is defined by a set of biologically distinct diseases characterized by maturation arrest and clonal proliferation of myeloid cells. Recommendations for post-remission therapy depend on assessing the leukemia risk characteristics, such as cytogenetics and molecular features present at diagnosis. Patients with high-risk disease include those whose leukemia is characterized by monosomal...
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