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Article

Slit2 is necessary for optic axon organization in the zebrafish ventral midline.

Cells & development - 1 Jun 2021

Davison Camila, Zolessi Flavio R

Abstract excerpt

Slit-Robo signaling has been implicated in regulating several steps of retinal ganglion cell axon guidance, with a central role assigned to Slit2. We report here the phenotypical characterization of a CRISPR-Cas9-generated zebrafish null mutant for this gene, along with a detailed analysis of its expression pattern by WM-FISH. All evident defects in the optic axons in slit2-/- mutants were detected outside the...

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Identifiers

PMID: 33994352
DOI: 10.1016/j.cdev.2021.203677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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