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(Automated) Synthesis of Well‐defined Staphylococcus Aureus Wall Teichoic Acid Fragments

14 May 2021

Abstract excerpt

Wall teichoic acids (WTAs) are important components of the cell wall of the opportunistic Gram-positive bacterium Staphylococcus aureus. WTAs are composed of repeating ribitol phosphate (RboP) residues that are decorated with d-alanine and N-acetyl-d-glucosamine (GlcNAc) modifications, in a seemingly random manner. These WTA-modifications play an important role in shaping the interactions of WTA with the host...

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PMID: 33991006
DOI: 10.1002/chem.202101242

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