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Structural investigation of humanS. aureus-targeting antibodies that bind wall teichoic acid

13 Aug 2018

Abstract excerpt

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a growing health threat worldwide. Efforts to identify novel antibodies that target S. aureus cell surface antigens are a promising direction in the development of antibiotics that can halt MRSA infection. We biochemically and structurally characterized three patient-derived MRSA-targeting antibodies that bind to wall teichoic acid (WTA),...

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PMID: 30102105
DOI: 10.1080/19420862.2018.1501252

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