Article
Evolutionary mechanisms and diversity in cancer.
Advances in cancer research - 1 Jan 2011
Heng Henry H Q, Stevens Joshua B, Bremer Steven W, Liu Guo, Abdallah Batoul Y, Ye Christine J
Abstract excerpt
The recently introduced genome theory of cancer evolution provides a new framework for evolutionary studies on cancer. In particular, the established relationship between the large number of individual molecular mechanisms and the general evolutionary mechanism of cancer calls upon a change in our strategies that have been based on the characterization of common cancer gene mutations and their defined pathways....
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