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Article

Functional study of TNF-α as a promoter of polymorphisms in psoriasis.

Italian journal of dermatology and venereology - 1 Apr 2022

Daprà Valentina, Ponti Renata, Lo Curcio Giada, Archetti Marialaura, Dini Maddalena, Gavatorta Martina, Quaglino Pietro, Fierro Maria T, Bergallo Massimiliano

Abstract excerpt

BACKGROUND: TNF-α is an important mediator in the pathogenesis of psoriasis and polymorphisms influence its transcription and could be implicated in psoriasis risk and modify certain aspects of disease, such as age at onset of psoriasis vulgaris and disease severity. Six TNF-α single nucleotide polymorphisms (SNPs) in promoter region has been identified and studied but with discordant results. The aim of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33982552
DOI: 10.23736/S2784-8671.21.06979-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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