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Article

TNFα gene polymorphisms in the pathogenesis of acne vulgaris.

Archives of dermatological research - 1 Jan 2011

Szabó Kornélia, Tax Gábor, Teodorescu-Brinzeu Dragos, Koreck Andrea, Kemény Lajos

Abstract excerpt

Inflammation plays an important role in acne pathogenesis, and pro-inflammatory cytokines are key factors in these events. Tumor necrosis factor alpha (TNFα) is a central molecule coded by a gene that shows high level of genetic polymorphisms especially in its promoter region. Single nucleotide polymorphisms (SNPs) of the TNFα gene have been shown to be associated with an increased risk to develop chronic...

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Identifiers

PMID: 20386917
DOI: 10.1007/s00403-010-1050-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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