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Article

Analysis of multiple genetic loci reveals MPDZ-NF1B rs1324183 as a putative genetic marker for keratoconus.

The British journal of ophthalmology - 1 Dec 2018

Wang Yu Meng, Ma Li, Lu Shi Yao, Chan Tommy Chung Yan, Yam Jason C S, Tang Shu Min, Kam Ka Wai, Tam Pancy O S, Tham Clement C, Young Alvin L, Jhanji Vishal, Pang Chi Pui, Chen Li Jia

Abstract excerpt

OBJECTIVE: To investigate the associations between 16 single-nucleotide polymorphisms (SNPs) in 14 genetic loci and keratoconus in an independent Chinese cohort. METHODS: This cross-sectional, case-control association study included a Chinese cohort of 133 patients with keratoconus and 371 control subjects. In a recent meta-analysis study, we identified association of 16 SNPs in 14 gene loci with keratoconus. In...

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PMID: 30002070
DOI: 10.1136/bjophthalmol-2018-312218

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MPDZ

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