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The role of microRNA-16 in the pathogenesis of autoimmune diseases: A comprehensive review

16 Feb 2019

Abstract excerpt

MicroRNAs (miRNAs) are a class of small noncoding RNAs that are only 21-25 nt long. Many studies have shown that miRNA dysfunction is closely related to the occurrence and development of diseases. By combining with the 3' noncoding region of target gene mRNA, miRNAs can mediate the degradation or translation inhibition of mRNA and exert a powerful regulation effect on gene expression at the posttranscriptional...

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PMID: 30780103
DOI: 10.1016/j.biopha.2019.01.044

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