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Article

The Mononuclear Phagocyte System of the Rat.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2021

Hume David A, Caruso Melanie, Keshvari Sahar, Patkar Omkar L, Sehgal Anuj, Bush Stephen J, Summers Kim M, Pridans Clare, Irvine Katharine M

Abstract excerpt

The laboratory rat continues to be the model of choice for many studies of physiology, behavior, and complex human diseases. Cells of the mononuclear phagocyte system (MPS; monocytes, macrophages, and dendritic cells) are abundant residents in every tissue in the body and regulate postnatal development, homeostasis, and innate and acquired immunity. Recruitment and proliferation of MPS cells is an essential...

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Identifiers

PMID: 33965905
DOI: 10.4049/jimmunol.2100136

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