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Developmental programming of tissue-resident macrophages

7 Nov 2024

Abstract excerpt

Macrophages are integral components of the innate immune system that colonize organs early in development and persist into adulthood through self-renewal. Their fate, whether they are replaced by monocytes or retain their embryonic origin, depends on tissue type and integrity. Macrophages are influenced by their environment, a phenomenon referred to as developmental programming. This influence extends beyond the...

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PMID: 39575254
DOI: 10.3389/fimmu.2024.1475369

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