Article
Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity.
Biological psychiatry - 15 Sept 2021
Clifton Nicholas E, Collado-Torres Leonardo, Burke Emily E, Pardiñas Antonio F, Harwood Janet C, Di Florio Arianna, Walters James T R, Owen Michael J, O'Donovan Michael C, Weinberger Daniel R, Holmans Peter A, Jaffe Andrew E, Hall Jeremy
Abstract excerpt
BACKGROUND: Recent breakthroughs in psychiatric genetics have implicated biological pathways onto which genetic risk for psychiatric disorders converges. However, these studies do not reveal the developmental time point(s) at which these pathways are relevant. METHODS: We aimed to determine the relationship between psychiatric risk and developmental gene expression relating to discrete biological pathways. We...
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