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Genetic Risk, BMI Status, BMI Change Patterns, and the Risk of Steatotic Liver Disease and Liver Enzyme Elevation in Chinese Adults.

Nutrients - 6 Dec 2024

Yang Juan, Tian Chan, Liu Maojie, Guo Haiyan, Lin Fei, Ding Yang, Yao Wentao, Zhang Jiahao, Fan Jingyi, Yu Chengxiao, Lu Jing, Zhang Qun

Abstract excerpt

Background/Objectives: Whether an increased genetic risk of steatotic liver disease (SLD) can be offset by maintaining a healthy weight remains unknown. We aimed to clarify the associations among the body mass index (BMI) and its change patterns with SLD and assess whether genetic susceptibility can modify these associations in Chinese people. Methods: A total of 10,091 and 6124 participants from the Health Omics...

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Identifiers

PMID: 39683606
DOI: 10.3390/nu16234212
PMCID: PMC11644279

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