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Article

Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques.

PLoS pathogens - 1 May 2021

Wood Matthew P, Jones Chloe I, Lippy Adriana, Oliver Brian G, Walund Brynn, Fancher Katherine A, Fisher Bridget S, Wright Piper J, Fuller James T, Murapa Patience, Habib Jakob, Mavigner Maud, Chahroudi Ann, Sather D Noah, Fuller Deborah H, Sodora Donald L

Abstract excerpt

HIV-infected infants are at an increased risk of progressing rapidly to AIDS in the first weeks of life. Here, we evaluated immunological and virological parameters in 25 SIV-infected infant rhesus macaques to understand the factors influencing a rapid disease outcome. Infant macaques were infected with SIVmac251 and monitored for 10 to 17 weeks post-infection. SIV-infected infants were divided into either...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33961680
DOI: 10.1371/journal.ppat.1009575
PMCID: PMC8133453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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