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Article

Incidence and Survival of IDH-Wildtype Glioblastoma and IDH-Mutant Astrocytoma by Treatment and Sex: A Regional Study in Spain (2011-2021).

Medical sciences (Basel, Switzerland) - 14 Oct 2025

Encarnación J A, Manso C, Royo-Villanova M, Ruiz P, De la Fuente M I, Cárdenas E, Ros S, Alonso-Romero J L

Abstract excerpt

BACKGROUND: The incidence and prognosis of high-grade gliomas differ according to histopathological and molecular features. The WHO 2021 CNS classification emphasized IDH status, but historical cohorts often lacked systematic molecular profiling. METHODS: We conducted a retrospective population-based study including adult patients diagnosed with IDH-wildtype glioblastoma or IDH-mutant astrocytoma in a Spanish...

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PMID: 41133515
DOI: 10.3390/medsci13040233
PMCID: PMC12551061

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