Article
Association between the -1562 C/T MMP-9 polymorphism and cerebrovascular disease in a Polish population.
Neurologia i neurochirurgia polska - 1 Jan 2000
Szczudlik Piotr, Borratyńska Anna
Abstract excerpt
BACKGROUND AND PURPOSE: Matrix metalloproteinase 9 (MMP-9) is an endopeptidase degrading extracellular matrix. There is growing evidence that changes in extracellular matrix play an important role in vascular pathology, especially in cardiovascular and cerebrovascular disease. Previous studies have demonstrated that MMP-9 activity is controlled by --1562 C/T polymorphism. Genotypes with T allele (CT, TT) have...
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