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Article

Biomarkers and heterogeneous fibroblast phenotype associated with incisional hernia.

Molecular and cellular biochemistry - 1 Sept 2021

Thankam Finosh G, Larsen Nicholas K, Varghese Ann, Bui Thao-Nguyen, Reilly Matthew, Fitzgibbons Robert J, Agrawal Devendra K

Abstract excerpt

Development of incisional hernia (IH) is multifactorial but inflammation and abdominal wall ECM (extracellular matrix) disorganization are key pathological events. We investigated if the differential expression of fibroblast biomarkers reflects the cellular milieu and the dysregulated ECM in IH tissues. Expression of fibroblast biomarkers, including connective tissue growth factor, alpha-smooth muscle actin...

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Identifiers

PMID: 33942219
DOI: 10.1007/s11010-021-04166-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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