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Article

Proinflammatory role of stem cells in abdominal aortic aneurysms.

Journal of vascular surgery - 1 Nov 2015

Ryer Evan J, Garvin Robert P, Schworer Charles M, Bernard-Eckroth Kamell R, Tromp Gerard, Franklin David P, Elmore James R, Kuivaniemi Helena

Abstract excerpt

OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) formation includes inflammation, vascular smooth muscle cell apoptosis, extracellular matrix degradation, and oxidative stress. That multipotent stem cells have an important role in cardiovascular health and disease has been well established, but the role of stem cells in aortic structural deterioration is poorly defined. We sought to describe the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24997808
DOI: 10.1016/j.jvs.2014.04.067

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