Article
Comprehensive mutational analysis of background mucosa in patients with Lugol-voiding lesions.
Cancer medicine - 1 Jun 2021
Akizue Naoki, Okimoto Kenichiro, Arai Makoto, Hirotsu Yosuke, Amemiya Kenji, Oura Hirotaka, Kaneko Tatsuya, Tokunaga Mamoru, Ishikawa Kentaro, Ohta Yuki, Taida Takashi, Saito Keiko, Maruoka Daisuke, Matsumura Tomoaki, Nakagawa Tomoo, Nishimura Motoi, Chiba Tetsuhiro, Matsushita Kazuyuki, Mochizuki Hitoshi, Yokosuka Osamu, Omata Masao, Kato Naoya
Abstract excerpt
Somatic mutations including the background mucosa in patients with Lugol-voiding lesions (LVLs) are still not well known. The aim of this study was to evaluate the somatic mutations of the background mucosa in patients with LVLs (Squamous cell carcinoma (SCC), intraepithelial neoplasia (IN), and hyperplasia). Twenty-five patients with LVLs (9 with SCC, 6 with IN, and 10 with hyperplasia) were included. A targeted...
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