Article
Targeting tumor associated macrophages (TAMs) via nanocarriers.
Journal of controlled release : official journal of the Controlled Release Society - 28 May 2017
Singh Yuvraj, Pawar Vivek Kumar, Meher Jaya Gopal, Raval Kavit, Kumar Animesh, Shrivastava Richa, Bhadauria Smrati, Chourasia Manish K
Abstract excerpt
Recruitment of inflammatory cells to tumor has been well documented, with the most frequent inhabitants being macrophages termed as tumor associated macrophages, (TAMs). Their presence was thought to be an evidence of immune system initiating a fight response towards the tumor, i.e. immune surveillance. This is the case too initially, when TAMs majorly exhibit an M1 phenotype, but their continued presence in...
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