Article
Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models.
International journal of molecular sciences - 27 Apr 2021
Gerussi Alessio, Natalini Ambra, Antonangeli Fabrizio, Mancuso Clara, Agostinetto Elisa, Barisani Donatella, Di Rosa Francesca, Andrade Raul, Invernizzi Pietro
Abstract excerpt
Drug-induced liver injury (DILI) is a challenging clinical event in medicine, particularly because of its ability to present with a variety of phenotypes including that of autoimmune hepatitis or other immune mediated liver injuries. Limited diagnostic and therapeutic tools are available, mostly because its pathogenesis has remained poorly understood for decades. The recent scientific and technological...
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