Article
Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation.
Expert review of molecular diagnostics - 1 Sept 2018
McGill Mitchell R, Jaeschke Hartmut
Abstract excerpt
INTRODUCTION: The difficulty of understanding and diagnosing drug-induced liver injury (DILI) has led to proliferation of serum and genetic biomarkers. Many applications of these biomarkers have been proposed, including investigation of mechanisms, prediction of DILI during early trials or before initiation of therapy in patients, and diagnosis of DILI during therapy. Areas covered: We review the definition and...
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