Article
Whole-exome sequencing of kidney transplant recipients and donors: insights into end-stage renal disease and post-transplant genetic risk.
BMC nephrology - 5 Nov 2025
Bayanova Mirgul, Bolatov Aidos, Malik Dias, Sapargaliyeva Malika, Abdikadirova Aizhan, Zhenissova Aida, Nazarova Lyazzat, Assykbayev Mels, Abdugafarov Saitkarim, Rakhimzhanova Saltanat, Suleimenova Deniza, Kuttymuratov Gani, Ainakulov Ardak, Sailybayeva Aliya, Altynova Sholpan, Pya Yuriy
Abstract excerpt
BACKGROUND: Kidney transplantation is the preferred treatment for end-stage renal disease (ESRD), yet challenges persist in long-term graft survival and post-transplant complications. Genomic profiling, especially whole-exome sequencing (WES), offers new opportunities to personalize donor-recipient matching and predict transplant outcomes. This study aimed to explore the genetic landscape of both transplant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.