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Article

Amoeba Predation of Cryptococcus neoformans Results in Pleiotropic Changes to Traits Associated with Virulence.

mBio - 27 Apr 2021

Fu Man Shun, Liporagi-Lopes Livia C, Dos Santos Samuel R, Tenor Jennifer L, Perfect John R, Cuomo Christina A, Casadevall Arturo

Abstract excerpt

Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil microbes such as Cryptococcus neoformans; these traits can also function in animal virulence by defeating phagocytic immune cells, such as macrophages. Consistent with this notion, incubation of various fungal species with amoebae enhanced their virulence, but the mechanisms involved are unknown. In this study, we exposed...

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Identifiers

PMID: 33906924
DOI: 10.1128/mBio.00567-21
PMCID: PMC8092252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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