Article
Adaptation to an amoeba host drives selection of virulence-associated traits and genetic variation in saprotrophic Candida albicans.
Frontiers in cellular and infection microbiology - 1 Jan 2024
Amsri Artid, Pruksaphon Kritsada, Thammasit Patcharin, Nosanchuk Joshua D, Youngchim Sirida
Abstract excerpt
Amoebae are micropredators that play an important role in controlling fungal populations in ecosystems. However, the interaction between fungi and their amoebic predators suggests that the pressure from predatory selection can significantly influence the development of fungal virulence and evolutionary processes. Thus, the purpose of this study was to investigate the adaptation of saprotrophic Candida albicans...
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