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Recurrent somatic mutations and low germline predisposition mutations in Korean ALL patients.

Scientific reports - 26 Apr 2021

Shin Sang-Yong, Lee Hyeonah, Lee Seung-Tae, Choi Jong Rak, Jung Chul Won, Koo Hong Hoe, Kim Sun-Hee

Abstract excerpt

In addition to somatic mutations, germline genetic predisposition to hematologic malignancies is currently emerging as an area attracting high research interest. In this study, we investigated genetic alterations in Korean acute lymphoblastic leukemia/lymphoma (ALL) patients using targeted gene panel sequencing. To this end, a gene panel consisting of 81 genes that are known to be associated with 23...

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Identifiers

PMID: 33903686
DOI: 10.1038/s41598-021-88449-4
PMCID: PMC8076247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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