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Article

Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis.

The Journal of investigative dermatology - 1 Dec 2016

Nousbeck Janna, Irvine Alan D

Abstract excerpt

In complex disease such as atopic dermatitis, the journey from identification of strong risk loci to profound functional and mechanistic insights can take several years. Here, Manz et al. have elegantly deciphered the mechanistic pathways in the well-established 11q13.5 atopic dermatitis risk locus. Their genetic and functional insights emphasize a role for T regulatory cells in atopic dermatitis pathogenesis.

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Source

Identifiers

PMID: 27884290
DOI: 10.1016/j.jid.2016.08.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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