Article

Spatial Proteomics Reveals Dual-Compartment Immune Evasion Architecture and Core Lymphomagenic Stromal Niches in Follicular Lymphoma

2026-06-11

Abstract excerpt

<h4>ABSTRACT</h4> Follicular lymphomas (FL) depend on microenvironmental signals for survival, and the composition of the tumor microenvironment may influence clinical outcome. How it is spatially organized, and how that organization drives immune evasion, has not been established. We applied two complementary 39-marker imaging mass cytometry panels to 156 follicular lymphoma tumor cores, generating a spatial atl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8cfc947d-cb60-55d4-a309-a5d6211d508e
DOI: 10.64898/2026.06.09.731209

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spatial Proteomics Reveals Dual-Compartment Immune Evasion Architecture and Core Lymphomagenic Stromal Niches in Follicular LymphomaDOI 10.64898/2026.06.09.731209Read

Revealing the Evolution of the Tumor Immune Microenvironment in Follicular Lymphoma Patients Progressing Within 24 Months Using Single-cell Imaging Mass CytometrySemantic proximity Read

Distinct follicular T cell subsets regulate lymphoma progression and outcomesSemantic proximity Read

Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic targetSemantic proximity Read

Immune microenvironment subtypes and association with tumor cell mutations and antigen expression in follicular lymphomaSemantic proximity Read

Advances in the multi-omics landscape of follicular lymphomaSemantic proximity Read

Single-cell spatial multi-omic characterization of the tumour microenvironment in transformed follicular lymphomaSemantic proximity Read

Follicular Lymphoma Microenvironment Characteristics Associated with Tumor Cell Mutations and MHC Class II ExpressionSemantic proximity Read

A Multi-scale, Multiomic Atlas of Human Normal and Follicular Lymphoma Lymph NodesSemantic proximity Read

Cell cross talk within the lymphoma tumor microenvironment: follicular lymphoma as a paradigmSemantic proximity Read

Biology as vulnerability in follicular lymphoma: genetics, epigenetics, and immunogeneticsSemantic proximity Read

Single Cell Spatial Analysis and Biomarker Discovery in Hodgkin LymphomaSemantic proximity Read

Analysis of intratumoral immune heterogeneity reveals spatial organisation of immunosuppression in breast cancerSemantic proximity Read