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Article

The Expansion of the PRAME Gene Family in Eutheria

10 Feb 2011

Abstract excerpt

The PRAME gene family belongs to the group of cancer/testis genes whose expression is restricted primarily to the testis and a variety of cancers. The expansion of this gene family as a result of gene duplication has been observed in primates and rodents. We analyzed the PRAME gene family in Eutheria and discovered a novel Y-linked PRAME gene family in bovine, PRAMEY, which underwent amplification after a...

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PMID: 21347312
DOI: 10.1371/journal.pone.0016867

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