Article
Role of ERβ in adipocyte metabolic response to wheel running following ovariectomy.
The Journal of endocrinology - 24 May 2021
Clart Laura M, Welly Rebecca J, Queathem Eric D, Rector R Scott, Padilla Jaume, Baines Christopher P, Kanaley Jill A, Lubahn Dennis B, Vieira-Potter Victoria J
Abstract excerpt
Estrogen receptor β (ERb), one of the two major estrogen receptors, acts via genomic and non-genomic signaling pathways to affect many metabolic functions, including mitochondrial biogenesis and respiration. This study assessed the effect of ERb classical genomic activity on adipocyte-specific and -systemic metabolic responses to wheel running exercise in a rodent model of menopause. Female mice lacking the ERb...
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